Coronary artery calcium is not universal: Population differences limit the global applicability
DOI:
https://doi.org/10.21542/gcsp.2026.16Abstract
To the Editor,
We read with considerable interest the recent meta-analysis by Al Hennawi et al., which synthesizes data from more than 240,000 individuals to evaluate the prognostic implications of coronary artery calcium (CAC) and its association with preventive therapies. The authors should be commended for addressing an important and timely topic. However, several key limitations warrant further discussion, particularly regarding the interpretation and global extrapolation of the findings.
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Copyright (c) 2026 Humberto Morais, Fidel Manuel Caceres-Loriga

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